nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron

Stable Identifier
R-HSA-174660
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
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nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron
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Circulating nascent chylomicrons acquire copies of apolipoproteins C-II, C-III, and E from circulating spherical (mature) high-density lipoprotein particles, becoming mature chylomicrons (Havel et al. 1973; Bisgaier and Glickman 1983). Here, this interaction is annotated to involve the transfer of a single copy of each lipoprotein, but a mature chylomicron in fact contains approximately 25 copies of apolipoprotein E and 180 copies of C apolipoproteins (Bhattacharya and Redgrave 1981).
Literature References
PubMed ID Title Journal Year
4345202 Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man

Havel, RJ, Kashyap, ML, Kane, JP

J Clin Invest 1973
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Orthologous Events
nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron (Bos taurus)
nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron (Canis familiaris)
nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron (Mus musculus)
nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron (Rattus norvegicus)
nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron (Sus scrofa)
Authored
D'Eustachio, P  (2008-05-12)
Reviewed
Jassal, B  (2008-06-13)
Created
D'Eustachio, P  (2006-02-20)
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