nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular]

Stable Identifier
R-HSA-174587
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Exocytosis of nascent chylomicrons
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While the export pathway for nascent chylomicrons has not been directly characterized in human cells, the requirement for SAR1B protein for normal chylomicron export in vivo (Jones et al. 2003) indicates that nascent chylomicrons are exported from the endoplasmic reticulum via the Golgi apparatus in COPII vesicles.

Literature References
PubMed ID Title Journal Year
12692552 Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders

Jones, B, Jones, EL, Bonney, SA, Patel, HN, Mensenkamp, AR, Eichenbaum-Voline, S, Rudling, M, Myrdal, U, Annesi, G, Naik, S, Meadows, N, Quattrone, A, Islam, SA, Naoumova, RP, Angelin, B, Infante, R, Levy, E, Roy, CC, Freemont, PS, Scott, J, Shoulders, CC

Nat Genet 2003
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