RFC dissociates after sliding clamp formation on the C-strand of the telomere

Stable Identifier
R-HSA-174447
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RFC dissociates after sliding clamp formation on the C-strand of the telomere
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It is assumed that, as shown for generic DNA replication (Podust et al. 1998), the RFC complex dissociates from PCNA following sliding clamp formation at the telomere, and the DNA toroid alone tethers pol delta to the DNA.
Literature References
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as an event of
Event Information
Go Biological Process
telomere maintenance via semi-conservative replication (0032201)
Orthologous Events
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Bos taurus)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Canis familiaris)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Mus musculus)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Rattus norvegicus)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Sus scrofa)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Xenopus tropicalis)
Authored
Blackburn, EH  (2006-03-10)
Seidel, J  (2006-03-10)
Reviewed
Gillespie, ME  (2020-01-03)
Hayashi, MT  (2020-04-29)
Price, C  (2006-07-13)
Created
Gillespie, ME  (2006-02-18)
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