The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere

Stable Identifier
R-HSA-174427
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The complementary strand is synthesized by the polymerase primase complex using conventional RNA priming (Dai et al. 2010).

Literature References
PubMed ID Title Journal Year
20639858 Molecular steps of G-overhang generation at human telomeres and its function in chromosome end protection

Dai, X, Huang, C, Bhusari, A, Sampathi, S, Schubert, K, Chai, W

EMBO J. 2010
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Catalyst Activity
Catalyst Activity
Title
DNA-directed DNA polymerase activity of DNA polymerase alpha:primase [nucleoplasm]
Physical Entity
Activity
Orthologous Events
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Created