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PAPSS1 [cytosol]
Stable Identifier
R-HSA-174387
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Bifunctional PAPS synthethase 1
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Cytosolic sulfonation of small molecules (Homo sapiens)
Transport and synthesis of PAPS (Homo sapiens)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Homo sapiens)
PAPSS1,2 [cytosol] (Homo sapiens)
PAPSS1 [cytosol] (Homo sapiens)
PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Homo sapiens)
PAPSS1,2 [cytosol] (Homo sapiens)
PAPSS1 [cytosol] (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Selenoamino acid metabolism (Homo sapiens)
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se (Homo sapiens)
APSe is phosphorylated to PAPSe by PAPSS1,2 (Homo sapiens)
PAPSS1,2 [cytosol] (Homo sapiens)
PAPSS1 [cytosol] (Homo sapiens)
H2SeO4 is converted to APSe by PAPSS1,2 (Homo sapiens)
PAPSS1,2 [cytosol] (Homo sapiens)
PAPSS1 [cytosol] (Homo sapiens)
Metabolism of carbohydrates and carbohydrate derivatives (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Transport and synthesis of PAPS (Homo sapiens)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Homo sapiens)
PAPSS1,2 [cytosol] (Homo sapiens)
PAPSS1 [cytosol] (Homo sapiens)
PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Homo sapiens)
PAPSS1,2 [cytosol] (Homo sapiens)
PAPSS1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43252 PAPSS1
Gene Names
PAPSS1, ATPSK1, PAPSS
Chain
chain:1-624
Reference Genes
BioGPS Gene:9061 PAPSS1
COSMIC (genes):PAPSS1 PAPSS1
CTD Gene:9061 PAPSS1
dbSNP Gene:9061 PAPSS1
ENSEMBL:ENSG00000138801 PAPSS1
HGNC:8603 PAPSS1
KEGG:hsa:9061 PAPSS1
Monarch:9061 PAPSS1
NCBI Gene:9061 PAPSS1
OMIM:603262 PAPSS1
UCSC:O43252 PAPSS1
Reference Transcript
RefSeq:XM_011532401.1 PAPSS1
RefSeq:XM_011532400.1 PAPSS1
RefSeq:NM_005443.4 PAPSS1
Other Identifiers
11727372_at
11727373_s_at
11751595_a_at
16978793
209043_PM_at
209043_at
2781001
2781002
2781003
2781004
2781005
2781019
2781020
2781022
2781024
2781025
2781026
2781027
2781028
2781029
2781030
2781031
2781032
2781033
2781034
2781035
2781037
2781039
2781040
2781041
2781042
34411_at
8102214
9061
A_23_P144465
GE54804
GO:0000103
GO:0001501
GO:0003824
GO:0004020
GO:0004781
GO:0005515
GO:0005524
GO:0005829
GO:0006790
GO:0009152
GO:0016301
GO:0016740
GO:0016779
GO:0034030
GO:0034033
GO:0042803
GO:0048856
GO:0050428
GO:0055086
GO:1901135
HMNXSV003000466
ILMN_1781819
ILMN_2224103
PH_hs_0027050
TC04001455.hg
g3378100_3p_at
Participates
as a member of
PAPSS1,2 [cytosol] (Homo sapiens)
Other forms of this molecule
PAPSS1(1-223)-BRAF(381-766) fusion [cytosol]
PAPSS1(1-223)-p-BRAF(381-766) fusion [cytosol]
Inferred To
papss1 [cytosol]
(Danio rerio)
papss1 [cytosol]
(Xenopus tropicalis)
Papss1 [cytosol]
(Rattus norvegicus)
PAPSS1 [cytosol]
(Bos taurus)
PAPSS1 [cytosol]
(Caenorhabditis elegans)
PAPSS1 [cytosol]
(Canis familiaris)
PAPSS1 [cytosol]
(Gallus gallus)
PAPSS1 [cytosol]
(Mus musculus)
PAPSS1 [cytosol]
(Saccharomyces cerevisiae)
PAPSS1 [cytosol]
(Schizosaccharomyces pombe)
PAPSS1 [cytosol]
(Sus scrofa)
Papss [cytosol]
(Drosophila melanogaster)
Cross References
ENSEMBL
ENSP00000265174
,
ENST00000265174
,
ENSG00000138801
OpenTargets
ENSG00000138801
GeneCards
PAPSS1
HPA
ENSG00000138801-PAPSS1
PRO
O43252
Pharos - Targets
O43252
GlyGen
O43252
HMDB Protein
HMDBP00345
PDB
1XJQ
,
2OFX
,
1XNJ
,
2PEY
,
2OFW
,
2PEZ
,
2QJF
,
8I1M
,
1X6V
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P02675 FGB
5
FGB [extracellular region]
(R-HSA-140584)
FGB(31-44) [extracellular region]
(R-HSA-140876)
FGB [plasma membrane]
(R-HSA-140917)
FGB(31-491) [extracellular region]
(R-HSA-140846)
FGB(31-491) [platelet alpha granule lumen]
(R-HSA-140921)
0.527
2
UniProt:O15287 FANCG
2
FANCG [cytosol]
(R-HSA-420788)
FANCG [nucleoplasm]
(R-HSA-419532)
0.527
2
UniProt:Q8WVK2 SNRNP27
1
SNRNP27 [nucleoplasm]
(R-HSA-6806778)
0.527
2
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