Phosphorylation of Cdh1 by Cyclin B1:Cdc2

Stable Identifier
R-HSA-174251
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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At the onset of mitosis, Cdh1 is phosphorylated by Cyclin B-Cdc2 resulting in a conformational change that prevents Cdh1 from activating the APC/C.

Literature References
PubMed ID Title Journal Year
11598127 Regulation of the anaphase-promoting complex by the dual specificity phosphatase human Cdc14a

Bembenek, J, Yu, H

J Biol Chem 2001
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
cyclin-dependent protein serine/threonine kinase activity of CCNB1:p-T161-CDK1 [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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