Reactome | UBE2C [cytosol]

UBE2C [cytosol]

Stable Identifier

R-HSA-174244

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

UbcH10, UbcX, E2-C

Locations in the PathwayBrowser

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Cell Cycle (Homo sapiens)

- Cell Cycle Checkpoints (Homo sapiens)
  - Mitotic Spindle Checkpoint (Homo sapiens)
    - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Homo sapiens)
      - Inactivation of APC/C via direct inhibition of the APC/C complex (Homo sapiens)
        
        Binding of the MCC complex to the APC/C complex (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
- Cell Cycle, Mitotic (Homo sapiens)
  - M Phase (Homo sapiens)
    - Mitotic Metaphase and Anaphase (Homo sapiens)
      - Mitotic Anaphase (Homo sapiens)
        
        Separation of Sister Chromatids (Homo sapiens)
        
        Association of Securin with Cdc20:APC/C complex (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Degradation of multiubiquitinated Securin (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Homo sapiens)
        
        CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
  - Regulation of mitotic cell cycle (Homo sapiens)
    - APC/C-mediated degradation of cell cycle proteins (Homo sapiens)
      - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Homo sapiens)
        
        APC/C:Cdh1 polyubiquitinates SKP2 (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Association of cell cycle proteins with the APC/C:Cdh1 complex (Homo sapiens)
        
        (APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        (APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Degradation of multiubiquitinated cell cycle proteins (Homo sapiens)
        
        multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        (APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Homo sapiens)
        
        cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        (APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        (APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
      - Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Homo sapiens)
        
        APC/C:Cdc20 mediated degradation of mitotic proteins (Homo sapiens)
        
        APC/C:Cdc20 mediated degradation of Cyclin B (Homo sapiens)
        
        Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Degradation of multiubiquitinated Cyclin B (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Homo sapiens)
        
        Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Homo sapiens)
        
        Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Homo sapiens)
        
        Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        APC/C:Cdc20 mediated degradation of Securin (Homo sapiens)
        
        Association of Securin with Cdc20:APC/C complex (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Degradation of multiubiquitinated Securin (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Homo sapiens)
        
        CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Homo sapiens)
        
        APC-Cdc20 mediated degradation of Nek2A (Homo sapiens)
        
        Association of Nek2A with MCC:APC/C (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Degradation of multiubiquitinated Nek2A (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Multiubiquitinated Nek2A [cytosol] (Homo sapiens)
        
        Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Multiubiquitination of Nek2A (Homo sapiens)
        
        Multiubiquitinated Nek2A [cytosol] (Homo sapiens)
        
        Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Homo sapiens)
        
        Association of Cyclin A with the APC/C (Homo sapiens)
        
        Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Degradation multiubiquitinated Cyclin A (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Homo sapiens)
        
        Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Homo sapiens)
        
        Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Homo sapiens)
        
        Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
      - Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Homo sapiens)
        
        Association of Cdh1 with the APC/C (Homo sapiens)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        Dissociation of Cdc20 from APC/C complex (Homo sapiens)
        
        CDC20:p-APC/C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
      - Regulation of APC/C activators between G1/S and early anaphase (Homo sapiens)
        
        Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Homo sapiens)
        
        Inactivation of APC/C via direct inhibition of the APC/C complex (Homo sapiens)
        
        Binding of the MCC complex to the APC/C complex (Homo sapiens)
        
        MCC:APC/C complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)
  - S Phase (Homo sapiens)
    - Synthesis of DNA (Homo sapiens)
      - Switching of origins to a post-replicative state (Homo sapiens)
        
        CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)
        
        Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Homo sapiens)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Protein ubiquitination (Homo sapiens)
    - Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Homo sapiens)
      - UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Homo sapiens)
        
        E2 ubiquitin conjugating enzyme (UBA1 substrate) [cytosol] (Homo sapiens)
        
        UBE2C [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:O00762 UBE2C

Gene Names

UBE2C, UBCH10

Chain

initiator methionine:, chain:2-179

Reference Genes

BioGPS Gene:11065 UBE2C

COSMIC (genes):UBE2C UBE2C

CTD Gene:11065 UBE2C

dbSNP Gene:11065 UBE2C

ENSEMBL:ENSG00000175063 UBE2C

HGNC:15937 UBE2C

KEGG:hsa:11065 UBE2C

Monarch:11065 UBE2C

NCBI Gene:11065 UBE2C

OMIM:605574 UBE2C

UCSC:O00762 UBE2C

Reference Transcript

Other Identifiers

11065

11724328_a_at

11733695_a_at

11733696_x_at

11733702_x_at

1651_at

16914315

202954_PM_at

202954_at

3587064

3887050

3887051

3887052

3887053

3887054

3887058

3887059

3887061

3887062

3887063

3887064

3887066

3887067

3887068

8063043

A_14_P116706

A_24_P297539

GE59386

GO:0000151

GO:0000209

GO:0003824

GO:0004842

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005680

GO:0005829

GO:0005886

GO:0006511

GO:0010458

GO:0010994

GO:0016567

GO:0016740

GO:0019787

GO:0030071

GO:0030163

GO:0031145

GO:0031536

GO:0032446

GO:0043161

GO:0043226

GO:0044389

GO:0045842

GO:0051301

GO:0061630

GO:0061631

GO:0065003

GO:0070936

GO:0070979

GO:0140096

GO:1904668

HMNXSV003018234

ILMN_1714730

ILMN_2265654

ILMN_2301083

PH_hs_0005126

PH_hs_0031411

TC20000357.hg

U73379_at

g5902145_3p_at

Participates

as a member of

as a candidate of

E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)

as a component of

phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)

Other forms of this molecule

UBE2C [nucleoplasm]

Ub-C114-UBE2C [nucleoplasm]

Ub-C114-UBE2C [cytosol]

Inferred To

UBE2C [cytosol] (Bos taurus)

UBE2C [cytosol] (Canis familiaris)

UBE2C [cytosol] (Sus scrofa)

Ube2c [cytosol] (Mus musculus)

Ube2c [cytosol] (Rattus norvegicus)

UBE2U [cytosol] (Gallus gallus)

ubc11 [cytosol] (Schizosaccharomyces pombe)

Ghost homologue of UBE2C [cytosol] (Caenorhabditis elegans)

Ghost homologue of UBE2C [cytosol] (Xenopus tropicalis)

vih [cytosol] (Drosophila melanogaster)

UBC11 [cytosol] (Saccharomyces cerevisiae)

ube2c [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_001268671.1, NP_861516.1, NP_001268670.1, NP_861515.1, NP_861517.1, NP_008950.1

OpenTargets

ENSG00000175063

ENSEMBL

ENSP00000348838, ENSP00000361649, ENSP00000333975, ENST00000352551, ENST00000335046, ENSP00000335674, ENST00000356455, ENST00000372568

HPA

ENSG00000175063-UBE2C

PRO

O00762

Pharos - Targets

O00762

PDB

4YII, 5A31, 8TAR, 5L9U, 1I7K, 5KHR, 8TAU

HMDB Protein

HMDBP00649

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13164 MAPK7	4	p-T218,Y221-MAPK7 [nucleoplasm] (R-HSA-198738) p-T218,Y221-MAPK7 [cytosol] (R-HSA-198721) MAPK7 [cytosol] (R-HSA-198754) MAPK7 [nucleoplasm] (R-HSA-199961)	0.556	3

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