Dissociation of phospho-Cdh1 from the APC/C complex

Stable Identifier
R-HSA-174139
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
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Following its phosphorylation, Cdh1 dissociates from the APC/C, rendering the APC/C inactive. This allows the stabilization of proteins required for subsequent cell cycle progression.

Literature References
PubMed ID Title Journal Year
10548110 Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex

Lukas, C, Sorensen, CS, Kramer, E, Santoni-Rugiu, E, Lindeneg, C, Peters, JM, Lukas, J

Nature 1999
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Orthologous Events
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