Association of Securin with Cdc20:APC/C complex

Stable Identifier
R-HSA-174121
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Association of Securin with Cdc20:APC/C complex
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Securin is thought to be recognized by the APC/C:Cdc20 complex through its conserved D-box sequence.

Literature References
PubMed ID Title Journal Year
12070128 Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1

Pines, J, Vodermaier, HC, Peters, JM, Den Elzen, N, Hagting, A, Waizenegger, IC

J Cell Biol 2002
Participants
Input
Output
Participates
as an event of
Orthologous Events
Association of Securin with Cdc20:APC/C complex (Bos taurus)
Association of Securin with Cdc20:APC/C complex (Canis familiaris)
Association of Securin with Cdc20:APC/C complex (Danio rerio)
Association of Securin with Cdc20:APC/C complex (Gallus gallus)
Association of Securin with Cdc20:APC/C complex (Mus musculus)
Association of Securin with Cdc20:APC/C complex (Rattus norvegicus)
Association of Securin with Cdc20:APC/C complex (Sus scrofa)
Association of Securin with Cdc20:APC/C complex (Xenopus tropicalis)
Authored
Castro, A  (2006-01-26)
Lorca, T  (2006-01-26)
Reviewed
Peters, JM  (2006-03-28)
Created
Matthews, L  (2006-02-17)
Cite Us!