Association of Securin with Cdc20:APC/C complex

Stable Identifier
R-HSA-174121
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Securin is thought to be recognized by the APC/C:Cdc20 complex through its conserved D-box sequence.

Literature References
PubMed ID Title Journal Year
12070128 Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1

Hagting, A, Den Elzen, N, Vodermaier, HC, Waizenegger, IC, Peters, JM, Pines, J

J Cell Biol 2002
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created