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Association of Cdh1 with the APC/C
Stable Identifier
R-HSA-174070
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Regulation of mitotic cell cycle (Homo sapiens)
APC/C-mediated degradation of cell cycle proteins (Homo sapiens)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Homo sapiens)
Association of Cdh1 with the APC/C (Homo sapiens)
General
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SBGN
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Following its dephosphorylation in late mitosis, Cdh1 replaces Cdc20 as the APC/C activator.
Literature References
PubMed ID
Title
Journal
Year
10793135
Mitotic regulation of the APC activator proteins CDC20 and CDH1
Podtelejnikov, AV
,
Scheuringer, N
,
Peters, JM
,
Kramer, ER
,
Mann, M
Mol Biol Cell
2000
Participants
Input
FZR1 [cytosol]
(Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol]
(Homo sapiens)
Output
phospho-APC/C:Cdh1 complex [cytosol]
(Homo sapiens)
Participates
as an event of
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Homo sapiens)
Orthologous Events
Association of Cdh1 with the APC/C (Bos taurus)
Association of Cdh1 with the APC/C (Canis familiaris)
Association of Cdh1 with the APC/C (Dictyostelium discoideum)
Association of Cdh1 with the APC/C (Drosophila melanogaster)
Association of Cdh1 with the APC/C (Gallus gallus)
Association of Cdh1 with the APC/C (Mus musculus)
Association of Cdh1 with the APC/C (Rattus norvegicus)
Association of Cdh1 with the APC/C (Sus scrofa)
Association of Cdh1 with the APC/C (Xenopus tropicalis)
Authored
Castro, A (2006-01-26)
Lorca, T (2006-01-26)
Reviewed
Peters, JM (2006-03-28)
Created
Matthews, L (2006-02-17)
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