Multiubiquitination of APC/C-associated Cdh1

Stable Identifier
R-HSA-174057
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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Cdh1 is multiubiquitinated by the APC/C:Cdh1 complex prior to degradation by the 26S proteasome.

Literature References
PubMed ID Title Journal Year
15029244 Mammalian Cdh1/Fzr mediates its own degradation

Listovsky, T, Oren, YS, Yudkovsky, Y, Mahbubani, HM, Weiss, AM, Lebendiker, M, Brandeis, M

EMBO J 2004
Participants
Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
ubiquitin-protein transferase activity of phospho-Cdh1:phospho-APC/C complex [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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