Reactome | CFB(26-259) [extracellular region]

CFB(26-259) [extracellular region]

Stable Identifier

R-HSA-173744

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Complement Factor Ba

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P00751 CFB

Gene Names

CFB, BF, BFD

Chain

signal peptide:1-25, chain:26-764, chain:26-259, chain:260-764

Reference Genes

BioGPS Gene:629 CFB

COSMIC (genes):CFB CFB

CTD Gene:629 CFB

dbSNP Gene:629 CFB

ENSEMBL:ENSG00000239754 CFB

ENSEMBL:ENSG00000241253 CFB

ENSEMBL:ENSG00000241534 CFB

ENSEMBL:ENSG00000242335 CFB

ENSEMBL:ENSG00000243570 CFB

ENSEMBL:ENSG00000243649 CFB

ENSEMBL_homo_sapiens_GENE:ENSG00000239754.9 CFB

ENSEMBL_homo_sapiens_GENE:ENSG00000241253.8 CFB

ENSEMBL_homo_sapiens_GENE:ENSG00000241534.9 CFB

ENSEMBL_homo_sapiens_GENE:ENSG00000242335.8 CFB

ENSEMBL_homo_sapiens_GENE:ENSG00000243570.9 CFB

ENSEMBL_homo_sapiens_GENE:ENSG00000243649.10 CFB

HGNC:1037 CFB

KEGG Gene (Homo sapiens):629 CFB

Monarch:629 CFB

NCBI Gene:629 CFB

OMIM:138470 CFB

UCSC:P00751 CFB

Reference Transcript

RefSeq:NM_001710.5 CFB

Other Identifiers

11733725_a_at

11744331_a_at

11749355_a_at

17006949

202357_3p_s_at

202357_PM_s_at

202357_s_at

2902837

2902846

2902848

2902849

2902852

2902853

2902854

2902855

2902856

2902858

2902859

2902861

2902864

2902867

2902868

2902870

2902871

2902872

2902875

2902876

2902877

2902880

2902881

2902882

2902883

35822_at

629

8118345

8178115

8179351

A_14_P116860

A_23_P156687

A_32_P162183

GE62019

GO:0001848

GO:0002376

GO:0003824

GO:0004252

GO:0005515

GO:0005576

GO:0005601

GO:0005615

GO:0005886

GO:0006508

GO:0006956

GO:0006957

GO:0008233

GO:0008236

GO:0009617

GO:0016787

GO:0043226

GO:0045087

GO:0070062

GO:0072562

GO:0098542

GO:0140096

HMNXSV003050772

ILMN_1774287

L15702_at

PH_hs_0004112

TC06004077.hg

TC6_cox_hap2000245.hg

TC6_dbb_hap3000222.hg

TC6_mann_hap4000196.hg

TC6_mcf_hap5000213.hg

TC6_qbl_hap6000225.hg

TC6_ssto_hap7000199.hg

g4502396_3p_at

g4502396_3p_s_at

g4502396_3p_x_at

p33713

Participates

as an output of

Other forms of this molecule

CFB(26-764) [extracellular region]

CFB(260-764) [plasma membrane]

CFB(260-764) [extracellular region]

Inferred To

Bf-2 [extracellular region] (Danio rerio)

cfb [extracellular region] (Xenopus tropicalis)

Homologues of CFB(26-259) [extracellular region] (Danio rerio)

Cfb [extracellular region] (Mus musculus)

CFB [extracellular region] (Bos taurus)

CFB [extracellular region] (Canis familiaris)

CFB [extracellular region] (Sus scrofa)

CFB(26-259) [extracellular region] (Gallus gallus)

fc04c04 [extracellular region] (Danio rerio)

Cross References

RefSeq

NP_001701.2

Guide to Pharmacology - Targets

2339

OpenTargets

ENSG00000243649

ZINC - Substances

CFAB_HUMAN

ZINC target

P00751

PRO

P00751

PDB

7JTQ, 6RAV, 2XWB, 7NOZ, 6T8V, 1RRK, 6T8W, 1DLE, 6RUR, 1Q0P, 2OK5, 6QSW, 2XWJ, 2WIN, 6QSX, 6RUV, 8ENU, 3HS0, 1RTK, 8EOK, 1RS0, 3HRZ, 6T8U, 7JTN

HPA

ENSG00000243649-CFB

GeneCards

P00751

Ensembl

ENSG00000243649, ENSP00000388352, ENST00000426239, ENSP00000411474, ENSG00000242335, ENST00000419920, ENST00000427888, ENST00000425368, ENSG00000243570, ENSG00000241253, ENSG00000241534, ENST00000436692, ENST00000455591, ENSP00000382862, ENST00000424727, ENST00000399981, ENSP00000389604, ENSP00000414341, ENST00000417261, ENSG00000239754, ENSP00000413351, ENSP00000391902, ENST00000419411, ENSP00000414889, ENSP00000416561, ENSP00000401719, ENSP00000411515, ENST00000433503

Pharos - Targets

P00751

Orphanet

17195

ZINC - Predictions - Purchasable

CFAB_HUMAN

Interactors (4)

Accession	Confidence Score	Evidence (IntAct)
IntAct:EBI-12735745 C3B	0.75	4
UniProt:Q92496-3 CFHR4	0.609	2
UniProt:Q91132 VCO3	0.57	3
UniProt:Q92496-1 CFHR4	0.544	2

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