C1Q:2x Activated C1R:2x Activated C1S

Stable Identifier
R-HSA-173615
Type
Complex
Species
Homo sapiens
Compartment
Synonyms
C1 with activated C1R, C1S
Locations in the PathwayBrowser
Summation

C1 is a calcium-dependent complex of C1q, R and S in the molar ratio of 1:2:2. C1q subcomponent is composed of nine subunits, six of which are disulfide-linked dimers of the A and B chains, and three of which are disulfide-linked dimers of the C chain.

Literature References
PubMed ID Title Journal Year
10904115 C1q: structure, function, and receptors

Kishore, U, Reid, KB

Immunopharmacology 2000
15388251 Structural and functional anatomy of the globular domain of complement protein C1q

Kishore, U, Ghai, R, Greenhough, TJ, Shrive, AK, Bonifati, DM, Gadjeva, MG, Waters, P, Kojouharova, MS, Chakraborty, T, Agrawal, A

Immunol Lett 2004
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