Reactome | UGDH [cytosol]

UGDH [cytosol]

Stable Identifier

R-HSA-173598

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

UDP-glucose dehydrogenase

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O60701 UGDH

Gene Names

UGDH

Chain

chain:1-494

Reference Genes

BioGPS Gene:7358 UGDH

COSMIC (genes):UGDH UGDH

CTD Gene:7358 UGDH

dbSNP Gene:7358 UGDH

ENSEMBL:ENSG00000109814 UGDH

HGNC:12525 UGDH

KEGG:hsa:7358 UGDH

Monarch:7358 UGDH

NCBI Gene:7358 UGDH

OMIM:603370 UGDH

UCSC:O60701 UGDH

Reference Transcript

Other Identifiers

11742854_x_at

11748627_x_at

16975310

203343_PM_at

203343_at

2766453

2766455

2766457

2766458

2766459

2766460

2766461

2766465

2766466

2766467

2766468

2766469

2766470

2766471

2766472

2766475

2766478

2766479

2766480

2766483

2766484

2766485

35214_at

7358

8099897

A_23_P167066

A_23_P167067

A_33_P3396607

GE54562

GO:0001702

GO:0003824

GO:0003979

GO:0005634

GO:0005654

GO:0005829

GO:0006024

GO:0006065

GO:0006790

GO:0015012

GO:0016491

GO:0016616

GO:0030206

GO:0034214

GO:0042802

GO:0043226

GO:0048666

GO:0048856

GO:0051287

GO:0055086

GO:0065003

GO:0070062

GO:1901135

HMNXSV003031779

ILMN_1729563

PH_hs_0002476

TC04001130.hg

TC04002517.hg

g4507812_3p_at

Participates

as a component of

6xUGDH [cytosol] (Homo sapiens)

Inferred To

UGDH [cytosol] (Bos taurus)

UGDH [cytosol] (Caenorhabditis elegans)

UGDH [cytosol] (Canis familiaris)

UGDH [cytosol] (Danio rerio)

UGDH [cytosol] (Drosophila melanogaster)

UGDH [cytosol] (Gallus gallus)

UGDH [cytosol] (Mus musculus)

UGDH [cytosol] (Rattus norvegicus)

UGDH [cytosol] (Sus scrofa)

UGDH [cytosol] (Xenopus tropicalis)

Cross References

OpenTargets

ENSG00000109814

ENSEMBL

ENSP00000426560, ENST00000506179, ENSP00000421757, ENST00000316423, ENST00000501493, ENST00000507089, ENSP00000422909, ENSP00000319501

IntEnz

1.1.1.22

HPA

ENSG00000109814-UGDH

PRO

O60701

Pharos - Targets

O60701

GlyGen

O60701

PDB

3TDK, 4RJT, 3PTZ, 6C4K, 6C58, 6C4J, 2Q3E, 3KHU, 3TF5, 5TJH, 6C5A, 2QG4, 4EDF, 3ITK, 3PRJ, 5VR8, 5W4X, 6C5Z

HMDB Protein

HMDBP00907

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	7

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