C1Q:2xC1R:2xC1S [extracellular region]

Stable Identifier
R-HSA-173584
Type
Complex
Species
Homo sapiens
Compartment
extracellular region
Synonyms
C1 complement factor
Locations in the PathwayBrowser
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General
C1 is a calcium-dependent complex of C1q, R and S in the molar ratio of 1:2:2. C1q subcomponent is composed of nine subunits, six of which are disulfide-linked dimers of the A and B chains, and three of which are disulfide-linked dimers of the C chain.
Literature References
PubMed ID Title Journal Year
15388251 Structural and functional anatomy of the globular domain of complement protein C1q

Kishore, U, Shrive, AK, Greenhough, TJ, Waters, P, Bonifati, DM, Kojouharova, MS, Gadjeva, MG, Chakraborty, T, Agrawal, A, Ghai, R

Immunol Lett 2004
10904115 C1q: structure, function, and receptors

Kishore, U, Reid, KB

Immunopharmacology 2000
Participants
components
Participates
as a component of
Inferred To
C1Q:2xC1R:2xC1S [extracellular region] (Bos taurus)
C1Q:2xC1R:2xC1S [extracellular region] (Canis familiaris)
C1Q:2xC1R:2xC1S [extracellular region] (Gallus gallus)
C1Q:2xC1R:2xC1S [extracellular region] (Mus musculus)
C1Q:2xC1R:2xC1S [extracellular region] (Rattus norvegicus)
C1Q:2xC1R:2xC1S [extracellular region] (Sus scrofa)
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