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C1QC [extracellular region]
Stable Identifier
R-HSA-173563
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Complement cascade (Homo sapiens)
Initial triggering of complement (Homo sapiens)
Conversion of C2 into C2a and C2b (Homo sapiens)
C4 activators [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
C1Q:2x Activated C1R:2x Activated C1S [extracellular region] (Homo sapiens)
C1Q [extracellular region] (Homo sapiens)
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
C1QC [extracellular region] (Homo sapiens)
Conversion of C4 into C4a and C4b (Homo sapiens)
C4 activators [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
C1Q:2x Activated C1R:2x Activated C1S [extracellular region] (Homo sapiens)
C1Q [extracellular region] (Homo sapiens)
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
C1QC [extracellular region] (Homo sapiens)
Creation of C4 and C2 activators (Homo sapiens)
Classical antibody-mediated complement activation (Homo sapiens)
Activation of C1r (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Homo sapiens)
C1Q:2x Activated C1R:2xC1S [extracellular region] (Homo sapiens)
C1Q [extracellular region] (Homo sapiens)
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
C1QC [extracellular region] (Homo sapiens)
Antigen:IgG:C1Q:2xC1R:2xC1S [plasma membrane] (Homo sapiens)
C1Q:2xC1R:2xC1S [extracellular region] (Homo sapiens)
C1Q [extracellular region] (Homo sapiens)
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
C1QC [extracellular region] (Homo sapiens)
C-reactive protein pentamer:phosphocholine:C1Q [extracellular region] (Homo sapiens)
C1Q [extracellular region] (Homo sapiens)
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
C1QC [extracellular region] (Homo sapiens)
Activation of C1s (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
C1Q:2x Activated C1R:2x Activated C1S [extracellular region] (Homo sapiens)
C1Q [extracellular region] (Homo sapiens)
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
C1QC [extracellular region] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Homo sapiens)
C1Q:2x Activated C1R:2xC1S [extracellular region] (Homo sapiens)
C1Q [extracellular region] (Homo sapiens)
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
C1QC [extracellular region] (Homo sapiens)
Regulation of Complement cascade (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Homo sapiens)
C1Q [extracellular region] (Homo sapiens)
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
C1QC [extracellular region] (Homo sapiens)
C1Q [extracellular region] (Homo sapiens)
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
C1QC [extracellular region] (Homo sapiens)
C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
C1Q:2x Activated C1R:2x Activated C1S [extracellular region] (Homo sapiens)
C1Q [extracellular region] (Homo sapiens)
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
C1QC [extracellular region] (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
C1Q:2x Activated C1R:2x Activated C1S [extracellular region] (Homo sapiens)
C1Q [extracellular region] (Homo sapiens)
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
C1QC [extracellular region] (Homo sapiens)
C1-Inh binds and inactivates C1r, C1s (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
C1Q:2x Activated C1R:2x Activated C1S [extracellular region] (Homo sapiens)
C1Q [extracellular region] (Homo sapiens)
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
C1QC [extracellular region] (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Homo sapiens)
C1Q [extracellular region] (Homo sapiens)
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
C1QC [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P02747 C1QC
Gene Names
C1QC, C1QG
Chain
signal peptide:1-28, chain:29-245
Reference Genes
BioGPS Gene:714 C1QC
COSMIC (genes):C1QC C1QC
CTD Gene:714 C1QC
dbSNP Gene:714 C1QC
ENSEMBL:ENSG00000159189 C1QC
HGNC:1245 C1QC
KEGG Gene (Homo sapiens):714 C1QC
Monarch:714 C1QC
NCBI Gene:714 C1QC
OMIM:120575 C1QC
UCSC:P02747 C1QC
Reference Transcript
RefSeq:NM_001114101.2 C1QC
RefSeq:NM_172369.4 C1QC
RefSeq:NM_001347619.1 C1QC
Other Identifiers
0002970372
11720388_s_at
16660581
225353_s_at
2324874
2324875
2324876
2324877
2324878
2324879
2324880
2324881
46705_at
714
7898799
A_14_P106837
A_23_P125977
GE79267
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005576
GO:0005581
GO:0005615
GO:0006950
GO:0006955
GO:0006956
GO:0006958
GO:0008150
GO:0030154
GO:0030449
GO:0030853
GO:0031012
GO:0032991
GO:0034330
GO:0045087
GO:0045202
GO:0045650
GO:0048856
GO:0062023
GO:0072562
GO:0098794
GO:0098883
HMNXSV003049262
Hs.94953.0.A1_3p_a_at
ILMN_1785902
TC01000286.hg
Participates
as a component of
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region] (Homo sapiens)
Inferred To
C1QC [extracellular region]
(Bos taurus)
C1QC [extracellular region]
(Canis familiaris)
C1QC [extracellular region]
(Danio rerio)
Homologues of C1QC [extracellular region]
(Danio rerio)
c1qa [extracellular region]
(Danio rerio)
C1qc [extracellular region]
(Mus musculus)
C1qc [extracellular region]
(Rattus norvegicus)
c1qb [extracellular region]
(Danio rerio)
c1qc [extracellular region]
(Danio rerio)
C1QB [extracellular region]
(Gallus gallus)
Cross References
RefSeq
NP_758957.2
,
NP_001107573.1
,
NP_001334548.1
OpenTargets
ENSG00000159189
HPA
ENSG00000159189-C1QC
GeneCards
P02747
Ensembl
ENST00000374639
,
ENSP00000363770
,
ENSP00000363771
,
ENST00000374640
,
ENSG00000159189
,
ENSP00000363768
,
ENST00000374637
PRO
P02747
Pharos - Targets
P02747
Orphanet
18953
GlyGen
P02747
HMDB Protein
HMDBP07479
PDB
2JG8
,
2JG9
,
2WNV
,
5HZF
,
2WNU
,
6Z6V
,
6FCZ
,
1PK6
,
5HKJ
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