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Antigen:IgG [plasma membrane]
Stable Identifier
R-HSA-173552
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
FCGR3A-mediated IL10 synthesis (Homo sapiens)
Phosphorylation and activation of PLCG due to FCGR3A effect (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Complement cascade (Homo sapiens)
Initial triggering of complement (Homo sapiens)
Conversion of C2 into C2a and C2b (Homo sapiens)
C4 activators [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Conversion of C4 into C4a and C4b (Homo sapiens)
C4 activators [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Creation of C4 and C2 activators (Homo sapiens)
Classical antibody-mediated complement activation (Homo sapiens)
Activation of C1r (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2xC1R:2xC1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Activation of C1s (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Regulation of Complement cascade (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
C1-Inh binds and inactivates C1r, C1s (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
FCGR activation (Homo sapiens)
Cross-linking of FCGRIA with IgG-coated Ag (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG-Ag:FCGRIA:CD3G homodimer [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Cross-linking of FCGRIIA with IgG-coated Ag (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG-Ag:FCGRIIA [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Cross-linking of FCGRIIIA with IgG-coated Ag (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG-Ag:FCGRIIIA:CD3G/CD3Z dimers [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Phosphorylation of SYK by Src kinases (Homo sapiens)
clustered IgG-Ag:p-FCGRs:SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Recruitment of SYK to phosphorylated ITAMs (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Homo sapiens)
clustered IgG-Ag:FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
Activation of RAC1 by CRKII:DOCK180:ELMO (Homo sapiens)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Activation of RAC1 by VAV (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Phosphorylation of VAV (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Homo sapiens)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Recruitment of VAV1 to p-6Y-SYK (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Role of myosins in phagosome formation (Homo sapiens)
clustered IgG-Ag:p-FCGRs [phagocytic cup] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Role of phospholipids in phagocytosis (Homo sapiens)
PI3K binds to p-6Y-SYK (Homo sapiens)
PI3K:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
PI3K:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Phosphorylation and activation of PLCG (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Recruitment of PLCgamma to membrane (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Release of PLCG from FCGR (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
Participants
components
Antigen [plasma membrane]
IgG [extracellular region] (Homo sapiens)
Participant Of
output
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates
hasComponent
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane]
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane]
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region]
Antigen:IgG:C1Q:2xC1R:2xC1S [plasma membrane]
clustered IgG-Ag:FCGRs [plasma membrane]
clustered IgG-Ag:p-FCGRs [phagocytic cup]
clustered IgG-Ag:p-FCGRs [plasma membrane]
IgG-Ag:FCGRIA:CD3G homodimer [plasma membrane]
IgG-Ag:FCGRIIA [plasma membrane]
IgG-Ag:FCGRIIIA:CD3G/CD3Z dimers [plasma membrane]
input
Cross-linking of FCGRIA with IgG-coated Ag
Cross-linking of FCGRIIA with IgG-coated Ag
Cross-linking of FCGRIIIA with IgG-coated Ag
Inferred To
Antigen:IgG [plasma membrane] (Canis familiaris)
Antigen:IgG [plasma membrane] (Danio rerio)
Antigen:IgG [plasma membrane] (Gallus gallus)
Antigen:IgG [plasma membrane] (Mus musculus)
Antigen:IgG [plasma membrane] (Rattus norvegicus)
Antigen:IgG [plasma membrane] (Sus scrofa)
Antigen:IgG [plasma membrane] (Xenopus tropicalis)
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