LDL + LDLR => LDL:LDLR complex

Stable Identifier
R-HSA-171122
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Low density lipoprotein (LDL) particles associate with LDL receptors (LDLR) at the cell surface (Goldstein et al. 1979). This binding is mediated by the apoprotein B-100 component of the LDL particle, which binds LDLR with 1:1 stoichiometry (van Driel et al. 1989).
Literature References
PubMed ID Title Journal Year
2722848 Stoichiometric binding of low density lipoprotein (LDL) and monoclonal antibodies to LDL receptors in a solid phase assay

Goldstein, JL, Van Driel, IR, Brown, MS

J Biol Chem 1989
221835 Coated pits, coated vesicles, and receptor-mediated endocytosis

Goldstein, JL, Brown, MS, Anderson, RG

Nature 1979
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