LDL + LDLR => LDL:LDLR complex

Stable Identifier
R-HSA-171122
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Low density lipoprotein (LDL) particles associate with LDL receptors (LDLR) at the cell surface (Goldstein et al. 1979). This binding is mediated by the apoprotein B-100 component of the LDL particle, which binds LDLR with 1:1 stoichiometry (van Driel et al. 1989).

Literature References
PubMed ID Title Journal Year
221835 Coated pits, coated vesicles, and receptor-mediated endocytosis

Goldstein, JL, Anderson, RG, Brown, MS

Nature 1979
2722848 Stoichiometric binding of low density lipoprotein (LDL) and monoclonal antibodies to LDL receptors in a solid phase assay

Van Driel, IR, Brown, MS, Goldstein, JL

J Biol Chem 1989
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