Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
LDLR [endosome membrane] => LDLR [plasma membrane]
Stable Identifier
R-HSA-171087
Type
Reaction [transition]
Species
Homo sapiens
Compartment
endosome membrane
Synonyms
Recycling of LDLR to plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein clearance (Homo sapiens)
LDL clearance (Homo sapiens)
LDLR [endosome membrane] => LDLR [plasma membrane] (Homo sapiens)
General
SBML
|
BioPAX
Level 2
Level 3
|
PDF
SVG
|
PNG
Low
Medium
High
|
PPTX
|
SBGN
Click the image above or
here
to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
LDL receptors in the endosome membrane are quickly returned to the cell surface (Goldstein et al. 1979).
Literature References
PubMed ID
Title
Journal
Year
221835
Coated pits, coated vesicles, and receptor-mediated endocytosis
Goldstein, JL
,
Brown, MS
,
Anderson, RG
Nature
1979
Participants
Input
LDLR [endosome membrane]
(Homo sapiens)
Output
LDLR [plasma membrane]
(Homo sapiens)
Participates
as an event of
LDL clearance (Homo sapiens)
Orthologous Events
LDLR [endosome membrane] => LDLR [plasma membrane] (Bos taurus)
LDLR [endosome membrane] => LDLR [plasma membrane] (Caenorhabditis elegans)
LDLR [endosome membrane] => LDLR [plasma membrane] (Canis familiaris)
LDLR [endosome membrane] => LDLR [plasma membrane] (Danio rerio)
LDLR [endosome membrane] => LDLR [plasma membrane] (Drosophila melanogaster)
LDLR [endosome membrane] => LDLR [plasma membrane] (Mus musculus)
LDLR [endosome membrane] => LDLR [plasma membrane] (Rattus norvegicus)
LDLR [endosome membrane] => LDLR [plasma membrane] (Sus scrofa)
LDLR [endosome membrane] => LDLR [plasma membrane] (Xenopus tropicalis)
Authored
D'Eustachio, P (2007-04-30)
Created
D'Eustachio, P (2006-01-28)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text