Dissociation of the Gi alpha:G olf complex

Stable Identifier
R-HSA-170674
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
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Once the intrinsic GTPase hydrolyzes GTP to GDP, Galpha-i dissociates from adenylate cyclase, allowing it to re-associate with G-beta-gamma and starting a new cycle.

Literature References
PubMed ID Title Journal Year
7937899 Mechanism of GTP hydrolysis by G-protein alpha subunits

Kleuss, C, Raw, AS, Lee, E, Sprang, SR, Gilman, AG

Proc Natl Acad Sci U S A 1994
Participants
Participant Of
Orthologous Events
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Created