Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes

Stable Identifier
R-HSA-170145
Type
Pathway
Species
Homo sapiens
Compartment
nucleoplasm
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Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
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Cyclin A:Cdc2 complexes are detected in the nucleus earlier that cyclin B1:Cdc2 complexes and may play a role in the initial events in prophase. Inactivation of Cdc25B by proteasome-mediated degradation is dependent upon cyclin A:Cdc2-mediated phosphorylation (Cans et al, 1999)

Literature References
PubMed ID Title Journal Year
10363647 Proteasome-dependent degradation of human CDC25B phosphatase

Baldin, V, Cans, C, Ducommun, B

Mol Biol Rep 1999
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Matthews, L  (2005-12-23)
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