Reactome | Positive regulation by 'XPO1 [nucleoplasm]'

Positive regulation by 'XPO1 [nucleoplasm]'

Stable Identifier

R-HSA-170059

Type

PositiveRegulation

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
      - Respiratory syncytial virus (RSV) genome replication, transcription and translation (Homo sapiens)
        
        Maturation of hRSV A proteins (Homo sapiens)
        
        M dimer gets exported from nucleus (Homo sapiens)
        
        XPO1 [nucleoplasm]

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by NPAS4 (Homo sapiens)
      - NPAS4 regulates expression of target genes (Homo sapiens)
        
        NPAS4 translocates to the cytosol (Homo sapiens)
        
        XPO1 [nucleoplasm]

Regulation participants

Regulation type

PositiveRegulation

Regulated entity

M dimer gets exported from nucleus

Regulated entity

NPAS4 translocates to the cytosol

Regulated entity

Translocation of Cyclin B1:phospho-Cdc2 to the cytoplasm

Regulator

XPO1 [nucleoplasm]

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