MCM2-7 mediated fork unwinding

Stable Identifier
R-HSA-169468
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
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MCM2-7 mediated fork unwinding
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In budding yeast, all MCM proteins have been proved to be essential for elongation. The active form of this protein complex may be a heterohexamer. A subcomplex of MCM proteins consisting fo MCM4,6, and -7 has a weak helicase activity that may contribute to DNA unwinding.

Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
helicase activity of MCM2-7 [nucleoplasm]
Physical Entity
MCM2-7 [nucleoplasm]
Activity
helicase activity (0004386)
Inferred From
Yeast Mcm2-7 mediated fork unwinding (Saccharomyces cerevisiae)
Authored
Tye, BK  (2005-11-29)
Created
Gopinathrao, G  (2005-11-29)