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What is Reactome ?
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TLR1:TLR2 [plasma membrane]
Stable Identifier
R-HSA-168946
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of Immune System (Homo sapiens)
Diseases associated with the TLR signaling cascade (Homo sapiens)
IRAK4 deficiency (TLR2/4) (Homo sapiens)
Defective IRAK4 does not bind MyD88:MAL:BTK:activated TLR2/4 (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
MyD88 deficiency (TLR2/4) (Homo sapiens)
Defective MyD88 does not bind MAL(TIRAP):TLR2/4 (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Defective MyD88 does not oligomerize within the activated TLR2/4 complex (Homo sapiens)
MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
TLR2:TLR1 binds SARS-CoV-2 E pentamer (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR2:TLR1:E:S3:M:encapsidated SARS-CoV-2 genomic RNA: 7a:O-glycosyl 3a tetramer [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing-Cross presentation (Homo sapiens)
ER-Phagosome pathway (Homo sapiens)
IKKB phosphorylates SNAP23 (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Innate Immune System (Homo sapiens)
Antimicrobial peptides (Homo sapiens)
Defensins (Homo sapiens)
Beta defensins (Homo sapiens)
Beta defensin 103 activates TLR1:TLR2 (Homo sapiens)
Beta defensin 103:TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Regulation of TLR by endogenous ligand (Homo sapiens)
SFTPA/SFTPD binds TLR2:TLR1 (Homo sapiens)
SFTPA/SFTPD:TLR2:TLR1 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Toll Like Receptor 2 (TLR2) Cascade (Homo sapiens)
Toll Like Receptor TLR1:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
Activated TLR2/4 interacts with MAL (TIRAP) (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Activated TLR2/4:TIRAP interacts with BTK (Homo sapiens)
TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)
TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)
TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal (Homo sapiens)
IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex (Homo sapiens)
IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Multiple IRAK1 autophosphorylation steps (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
MyD88 forms a complex with TIRAP:activated TLR2/4 (Homo sapiens)
MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 (Homo sapiens)
MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex (Homo sapiens)
IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TIRAP is phosphorylated by BTK (Homo sapiens)
TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TRAF6 binds to hp- IRAK1 (Homo sapiens)
TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TRAF6 binds to p-IRAK2 (Homo sapiens)
TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1:TLR2 is recruited to ligand:CD14 (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Toll Like Receptor TLR6:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
Activated TLR2/4 interacts with MAL (TIRAP) (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Activated TLR2/4:TIRAP interacts with BTK (Homo sapiens)
TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)
TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)
TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal (Homo sapiens)
IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex (Homo sapiens)
IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Multiple IRAK1 autophosphorylation steps (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
MyD88 forms a complex with TIRAP:activated TLR2/4 (Homo sapiens)
MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 (Homo sapiens)
MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex (Homo sapiens)
IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TIRAP is phosphorylated by BTK (Homo sapiens)
TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TRAF6 binds to hp- IRAK1 (Homo sapiens)
TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TRAF6 binds to p-IRAK2 (Homo sapiens)
TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
Activated TLR2/4 interacts with MAL (TIRAP) (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Activated TLR2/4:TIRAP interacts with BTK (Homo sapiens)
TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)
TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)
TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal (Homo sapiens)
IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex (Homo sapiens)
IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Multiple IRAK1 autophosphorylation steps (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
MyD88 forms a complex with TIRAP:activated TLR2/4 (Homo sapiens)
MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 (Homo sapiens)
MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex (Homo sapiens)
IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TIRAP is phosphorylated by BTK (Homo sapiens)
TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TRAF6 binds to hp- IRAK1 (Homo sapiens)
TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TRAF6 binds to p-IRAK2 (Homo sapiens)
TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
17889651
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
Kim, HM
,
Kim, SE
,
Paik, SG
,
Lee, ME
,
Lee, JO
,
Lee, H
,
Heo, JY
,
Jin, MS
Cell
2007
Participants
components
TLR1 [plasma membrane]
(Homo sapiens)
TLR2 [plasma membrane]
(Homo sapiens)
Participates
as a component of
Beta defensin 103:TLR1:TLR2 [plasma membrane] (Homo sapiens)
SFTPA/SFTPD:TLR2:TLR1 [plasma membrane] (Homo sapiens)
TLR2:TLR1:E:S3:M:encapsidated SARS-CoV-2 genomic RNA: 7a:O-glycosyl 3a tetramer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
as an input of
Beta defensin 103 activates TLR1:TLR2 (Homo sapiens)
SFTPA/SFTPD binds TLR2:TLR1 (Homo sapiens)
TLR2:TLR1 binds SARS-CoV-2 E pentamer (Homo sapiens)
TLR1:TLR2 is recruited to ligand:CD14 (Homo sapiens)
Inferred To
TLR1:TLR2 [plasma membrane]
(Canis familiaris)
TLR1:TLR2 [plasma membrane]
(Gallus gallus)
TLR1:TLR2 [plasma membrane]
(Mus musculus)
TLR1:TLR2 [plasma membrane]
(Rattus norvegicus)
TLR1:TLR2 [plasma membrane]
(Sus scrofa)
Cross References
ComplexPortal
CPX-893
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