Binding of NS1 to dsRNA

Stable Identifier
R-HSA-168891
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Influenza A virus
Compartment
cytosol
ReviewStatus
5/5
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Binding of NS1 to dsRNA
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The ability of viral non-structural protein 1 (NS1) to sequester dsRNA is believed to be one of the primary mechanisms by which NS1 prevents activation of downstream anti-viral signaling pathways.

Literature References
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
mitigation of host antiviral defense response (0019049)
Disease
Name Identifier Synonyms
influenza DOID:8469 Influenza with other manifestations (disorder), Influenza with other manifestations NOS (disorder), flu, Influenza with other manifestations, Influenza with non-respiratory manifestation (disorder), influenza with non-respiratory manifestation
Authored
Gillespie, ME  (2013-11-18)
Reviewed
Gale M, Jr  (2004-05-12)
Created
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