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tBID bound to inactive BAX
Stable Identifier
R-HSA-168850
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Intrinsic Pathway for Apoptosis (Homo sapiens)
Activation, translocation and oligomerization of BAX (Homo sapiens)
tBID activates BAX protein (Homo sapiens)
tBID bound to inactive BAX [cytosol] (Homo sapiens)
tBID binds to inactive BAX protein (Homo sapiens)
tBID bound to inactive BAX [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
10950869
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c
Genes Dev
2000
Participants
components
BAX [cytosol] (Homo sapiens)
BID(62-195) [cytosol] (Homo sapiens)
Participant Of
input
tBID activates BAX protein
output
tBID binds to inactive BAX protein
Inferred To
tBID bound to inactive BAX [cytosol] (Bos taurus)
tBID bound to inactive BAX [cytosol] (Canis familiaris)
tBID bound to inactive BAX [cytosol] (Mus musculus)
tBID bound to inactive BAX [cytosol] (Rattus norvegicus)
tBID bound to inactive BAX [cytosol] (Sus scrofa)
tBID bound to inactive BAX [cytosol] (Taeniopygia guttata)
tBID bound to inactive BAX [cytosol] (Xenopus tropicalis)
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