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tBID bound to inactive BAK
Stable Identifier
R-HSA-168847
Type
Complex
Species
Homo sapiens
Compartment
mitochondrial outer membrane
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Intrinsic Pathway for Apoptosis (Homo sapiens)
Activation and oligomerization of BAK protein (Homo sapiens)
tBID activates BAK protein (Homo sapiens)
tBID bound to inactive BAK [mitochondrial outer membrane] (Homo sapiens)
tBID binds to inactive BAK protein (Homo sapiens)
tBID bound to inactive BAK [mitochondrial outer membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
10950869
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c
Genes Dev
2000
Participants
components
BAK1 [mitochondrial outer membrane] (Homo sapiens)
MYS-BID(62-195) [mitochondrial outer membrane] (Homo sapiens)
Participant Of
input
tBID activates BAK protein
output
tBID binds to inactive BAK protein
Inferred To
tBID bound to inactive BAK [mitochondrial outer membrane] (Bos taurus)
tBID bound to inactive BAK [mitochondrial outer membrane] (Canis familiaris)
tBID bound to inactive BAK [mitochondrial outer membrane] (Gallus gallus)
tBID bound to inactive BAK [mitochondrial outer membrane] (Mus musculus)
tBID bound to inactive BAK [mitochondrial outer membrane] (Rattus norvegicus)
tBID bound to inactive BAK [mitochondrial outer membrane] (Sus scrofa)
tBID bound to inactive BAK [mitochondrial outer membrane] (Taeniopygia guttata)
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