Virus Assembly and Release

Stable Identifier
R-HSA-168268
Type
Pathway
Species
Homo sapiens
Related Species
Influenza A virus
ReviewStatus
5/5
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Virus Assembly and Release
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Influenza viruses assemble and bud from the apical plasma membrane of polarized cells e.g. lung epithelial cells of the infected host. This asymmetrical process (i.e. apical [Influenza virus] or basolateral [Marburg virus]) is thought to have an important role in viral pathogenesis and tissue tropism. In most cases the individual viral envelope proteins are seen to accumulate at the same polar surface from which virus budding occurs, suggesting that they determine the maturation site
Literature References
PubMed ID Title Journal Year
0 Orthomyxoviridae: The Viruses and Their Replication

Shaw, ML, Palese, P

Fields Virology, 5th edition D.M. Knipe and P.M. Howley, Editors. 2006, Lippencott Williams and Wilkins: Philadelphia ISBN-10: 0-7817-6060-7 2001
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
viral life cycle (0019058)
Disease
Name Identifier Synonyms
influenza DOID:8469 Influenza with other manifestations (disorder), Influenza with other manifestations NOS (disorder), flu, Influenza with other manifestations, Influenza with non-respiratory manifestation (disorder), influenza with non-respiratory manifestation
Created
Gillespie, ME  (2005-11-14)
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