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HPSE2(1-592) [plasma membrane]
Stable Identifier
R-HSA-1678680
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
HPSE2, Heparanase-2, HPSE2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Heparan sulfate/heparin (HS-GAG) metabolism (Homo sapiens)
HS-GAG degradation (Homo sapiens)
Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Homo sapiens)
HPSE2(1-592) [plasma membrane] (Homo sapiens)
HPSE2:HS/HPIN-PGs [plasma membrane] (Homo sapiens)
HPSE2(1-592) [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8WWQ2 HPSE2
Gene Names
HPSE2, HPA2
Chain
signal peptide:1-41, chain:42-592
Reference Genes
BioGPS Gene:60495 HPSE2
COSMIC (genes):HPSE2 HPSE2
CTD Gene:60495 HPSE2
dbSNP Gene:60495 HPSE2
ENSEMBL:ENSG00000172987 HPSE2
HGNC:18374 HPSE2
KEGG:hsa:60495 HPSE2
Monarch:60495 HPSE2
NCBI Gene:60495 HPSE2
OMIM:613469 HPSE2
UCSC:Q8WWQ2 HPSE2
Reference Transcript
RefSeq:NM_001166245.1 HPSE2
RefSeq:NM_021828.4 HPSE2
RefSeq:NM_001166246.1 HPSE2
RefSeq:NM_001166244.1 HPSE2
Other Identifiers
11745399_a_at
16717342
220927_PM_s_at
220927_s_at
3302883
3302885
3302887
3302888
3302889
3302891
3302895
3302896
3302915
3302916
3302920
3302922
3302924
3302925
3302945
3302953
3302957
3302958
3302959
3302960
60495
7935613
85364_at
A_23_P61707
A_24_P103893
GE488396
GE553326
GO:0003824
GO:0005576
GO:0005615
GO:0005886
GO:0008150
GO:0008283
GO:0008284
GO:0016020
GO:0016787
GO:0016798
GO:0030198
GO:0030305
GO:0030312
GO:0031012
GO:0043395
HMNXSV003053781
ILMN_1732035
PH_hs_0027363
TC10001579.hg
g11141906_3p_a_at
Participates
as a component of
HPSE2:HS/HPIN-PGs [plasma membrane] (Homo sapiens)
as an input of
Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Homo sapiens)
Inferred To
Dmel\CG14309 [plasma membrane]
(Drosophila melanogaster)
hpse2 [plasma membrane]
(Xenopus tropicalis)
HPSE2(1-592) [plasma membrane]
(Gallus gallus)
Hpse2 [plasma membrane]
(Mus musculus)
Hpse2 [plasma membrane]
(Rattus norvegicus)
HPSE2 [plasma membrane]
(Bos taurus)
HPSE2 [plasma membrane]
(Canis familiaris)
HPSE2 [plasma membrane]
(Sus scrofa)
Cross References
ENSEMBL
ENST00000370546
,
ENSP00000359583
,
ENST00000370552
,
ENSP00000359580
,
ENST00000370549
,
ENSP00000485916
,
ENSP00000359577
,
ENST00000628193
OpenTargets
ENSG00000172987
HPA
ENSG00000172987-HPSE2
PRO
Q8WWQ2
Pharos - Targets
Q8WWQ2
GlyGen
Q8WWQ2
Orphanet
HPSE2
HMDB Protein
HMDBP11785
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