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IDUA [lysosomal lumen]
Stable Identifier
R-HSA-1678661
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Synonyms
Alpha-L-iduronidase, IDUA_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Chondroitin sulfate/dermatan sulfate metabolism (Homo sapiens)
CS/DS degradation (Homo sapiens)
IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS (Homo sapiens)
IDUA [lysosomal lumen] (Homo sapiens)
Heparan sulfate/heparin (HS-GAG) metabolism (Homo sapiens)
HS-GAG degradation (Homo sapiens)
IDUA hydrolyses Heparan sulfate chain(1) (Homo sapiens)
IDUA [lysosomal lumen] (Homo sapiens)
IDUA hydrolyses Heparan sulfate chain(6) (Homo sapiens)
IDUA [lysosomal lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P35475 IDUA
Gene Names
IDUA
Chain
signal peptide:1-27, chain:28-653
Reference Genes
BioGPS Gene:3425 IDUA
COSMIC (genes):IDUA IDUA
CTD Gene:3425 IDUA
dbSNP Gene:3425 IDUA
ENSEMBL:ENSG00000127415 IDUA
ENSEMBL_homo_sapiens_GENE:ENSG00000127415.13 IDUA
HGNC:5391 IDUA
KEGG Gene (Homo sapiens):3425 IDUA
Monarch:3425 IDUA
NCBI Gene:3425 IDUA
OMIM:252800 IDUA
UCSC:P35475 IDUA
Reference Transcript
RefSeq:NM_000203.4 IDUA
Other Identifiers
11744018_a_at
16963845
205057_PM_s_at
205057_s_at
205059_PM_s_at
205059_s_at
2714415
2714416
2714417
2714429
2714431
2714434
2714437
2714439
2714441
2714443
2714444
2714446
2714447
2714449
2714451
2714452
2714453
2714454
2714455
33155_at
3425
8093425
A_23_P167093
A_33_P3392087
GE60520
GO:0003824
GO:0003940
GO:0004553
GO:0005102
GO:0005576
GO:0005615
GO:0005764
GO:0005773
GO:0005975
GO:0005984
GO:0006027
GO:0006790
GO:0008152
GO:0016787
GO:0016798
GO:0030163
GO:0030200
GO:0030209
GO:0030211
GO:0043202
GO:0043226
GO:0070062
GO:1901135
HMNXSV003019884
Hs.89560.0.A1_3p_a_at
ILMN_1703041
M74715_s_at
M95740_at
PH_hs_0004997
TC04000015.hg
g4557660_3p_a_at
Other forms of this molecule
IDUA W402* [lysosomal lumen]
IDUA Q70* [lysosomal lumen]
IDUA P553R [lysosomal lumen]
Inferred To
idua [lysosomal lumen]
(Xenopus tropicalis)
Idua [lysosomal lumen]
(Rattus norvegicus)
Homologues of IDUA [lysosomal lumen]
(Canis familiaris)
IDUA [lysosomal lumen]
(Bos taurus)
IDUA [lysosomal lumen]
(Canis familiaris)
IDUA [lysosomal lumen]
(Dictyostelium discoideum)
IDUA [lysosomal lumen]
(Drosophila melanogaster)
IDUA [lysosomal lumen]
(Gallus gallus)
IDUA [lysosomal lumen]
(Mus musculus)
IDUA [lysosomal lumen]
(Sus scrofa)
Cross References
RefSeq
NP_000194.2
OpenTargets
ENSG00000127415
GeneCards
P35475
HPA
ENSG00000127415-IDUA
Ensembl
ENST00000247933
,
ENSG00000127415
,
ENST00000514224
,
ENSP00000247933
,
ENSP00000425081
PRO
P35475
Pharos - Targets
P35475
Orphanet
16240
HMDB Protein
HMDBP01593
PDB
4MJ2
,
6I6X
,
3W81
,
4KH2
,
3W82
,
4MJ4
,
6I6R
,
4KGL
,
4OBS
,
4KGJ
,
4OBR
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