At the Golgi membrane, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase (TPTE2) aka TPIP dephosphorylates phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) to produce phosphatidylinositol 4-phosphate (PI4P) (Tapparel et al. 2000, Walker et al. 2001). The transmembrane phosphatase TPTE2 gamma isoform colocalises in the Golgi and the endoplasmic reticulum (Tapparel et al. 2000).
Leslie, NR, Walker, SM, Downes, CP
Lyle, R, Tapparel, C, Antonarakis, SE, Guillou, L, Hutter, P, Reymond, A, Lamon, C, Girardet, C
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity of TPTE2-like proteins [Golgi membrane]
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