PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane

Stable Identifier
R-HSA-1675974
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Reaction
Species
Homo sapiens
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At the early endosome membrane, phosphatidylinositol 4-kinase type 2-alpha/beta (PI4K2A/B) (Balla et al. 2002) phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 4-phosphate (PI4P).

Literature References
PubMed ID Title Journal Year
11923287 Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments

Balla, T, Tuymetova, G, Balla, A, Barshishat, M, Geiszt, M

J Biol Chem 2002
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Catalyst Activity

1-phosphatidylinositol 4-kinase activity of PI4K2A/2B [cytosol]

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