At the Golgi membrane, phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha (PIK3C2A) (Domin et al. 2000, Arcaro et al. 2000) and phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma (PIK3C2G) (Ono et al. 1998, Rozycka et al. 1998, Misawa et al. 1998) phosphorylate phosphatidylinositol 4-phosphate (PI4P) to phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2). PIK3C2G phosphorylates phosphatidylinositol (PI) and PI4P but not phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2).
Domin, J, Gaidarov, I, Smith, ME, Keen, JH, Waterfield, MD
Arcaro, A, Zvelebil, MJ, Wallasch, C, Ullrich, A, Waterfield, MD, Domin, J
Rozycka, M, Lu, YJ, Brown, RA, Lau, MR, Shipley, JM, Fry, MJ
Ono, F, Nakagawa, T, Saito, S, Owada, Y, Sakagami, H, Goto, K, Suzuki, M, Matsuno, S, Kondo, H
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