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GNAT2 [plasma membrane]
Stable Identifier
R-HSA-167417
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
G protein alpha (T2), G(T2)
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Homo sapiens)
G-alpha(t)-GTP [plasma membrane] (Homo sapiens)
G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Homo sapiens)
G-alpha(t)-GTP [plasma membrane] (Homo sapiens)
G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
Opsins act as GEFs for G alpha-t (Homo sapiens)
G-alpha(t):GDP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Homo sapiens)
G-alpha(t)-GDP [plasma membrane] (Homo sapiens)
G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Homo sapiens)
G-alpha(t)-GTP [plasma membrane] (Homo sapiens)
G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
Opsins binds G alpha-t (Homo sapiens)
G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Homo sapiens)
G-alpha(t)-GDP [plasma membrane] (Homo sapiens)
G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
G-alpha(t):GDP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Homo sapiens)
G-alpha(t)-GDP [plasma membrane] (Homo sapiens)
G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
Signaling by WNT (Homo sapiens)
Beta-catenin independent WNT signaling (Homo sapiens)
Ca2+ pathway (Homo sapiens)
FZD recruits trimeric G-proteins (Homo sapiens)
Heterotrimeric G-protein (o/t2) (inactive) [plasma membrane] (Homo sapiens)
G-protein alpha (o/t2):GDP [plasma membrane] (Homo sapiens)
G-protein alpha (o/t2) [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
WNT5A/11:FZD:G-protein (alpha o/t2) inactive [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein (o/t2) (inactive) [plasma membrane] (Homo sapiens)
G-protein alpha (o/t2):GDP [plasma membrane] (Homo sapiens)
G-protein alpha (o/t2) [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
G alpha t2 binds and activates PDE6 (Homo sapiens)
GNAT2:GTP [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
GNAT2:PDE6 [plasma membrane] (Homo sapiens)
GNAT2:GTP [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
G-protein subunits dissociate from WNT:FZD complex (Homo sapiens)
G-protein alpha (o/t2) [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Homo sapiens)
G-protein alpha (o/t2):GTP [plasma membrane] (Homo sapiens)
G-protein alpha (o/t2) [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
PDE6 hydrolyses cGMP to GMP (Homo sapiens)
GNAT2:PDE6 [plasma membrane] (Homo sapiens)
GNAT2:GTP [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
WNT:FZD complex promotes G-protein nucleotide exchange (Homo sapiens)
WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Homo sapiens)
G-protein alpha (o/t2):GTP [plasma membrane] (Homo sapiens)
G-protein alpha (o/t2) [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
WNT5A/11:FZD:G-protein (alpha o/t2) inactive [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein (o/t2) (inactive) [plasma membrane] (Homo sapiens)
G-protein alpha (o/t2):GDP [plasma membrane] (Homo sapiens)
G-protein alpha (o/t2) [plasma membrane] (Homo sapiens)
GNAT2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P19087 GNAT2
Gene Names
GNAT2, GNATC
Chain
initiator methionine:, chain:2-354
Reference Genes
BioGPS Gene:2780 GNAT2
COSMIC (genes):GNAT2 GNAT2
CTD Gene:2780 GNAT2
dbSNP Gene:2780 GNAT2
ENSEMBL:ENSG00000134183 GNAT2
ENSEMBL_homo_sapiens_GENE:ENSG00000134183.13 GNAT2
HGNC:4394 GNAT2
KEGG Gene (Homo sapiens):2780 GNAT2
Monarch:2780 GNAT2
NCBI Gene:2780 GNAT2
OMIM:139340 GNAT2
Reference Transcript
RefSeq:XM_011541264.2 GNAT2
RefSeq:NM_005272.3 GNAT2
Other Identifiers
11736794_at
16690623
210604_PM_at
210604_at
2427171
2427172
2427173
2427174
2427175
2427176
2427178
2427181
2427183
2427184
2427185
2427186
2780
34571_at
7918367
A_23_P104012
A_33_P3409944
GE60358
GO:0000166
GO:0000902
GO:0001580
GO:0001664
GO:0001750
GO:0001917
GO:0003824
GO:0003924
GO:0005525
GO:0005834
GO:0005886
GO:0005929
GO:0006954
GO:0007165
GO:0007186
GO:0007188
GO:0007204
GO:0007601
GO:0007602
GO:0007632
GO:0008020
GO:0008104
GO:0009411
GO:0009416
GO:0009583
GO:0009642
GO:0010467
GO:0014070
GO:0016020
GO:0016787
GO:0019001
GO:0023052
GO:0030154
GO:0031683
GO:0042417
GO:0042622
GO:0042670
GO:0042995
GO:0043010
GO:0043226
GO:0045202
GO:0046549
GO:0046872
GO:0048771
GO:0048856
GO:0048877
GO:0050877
GO:0050896
GO:0050908
GO:0051938
GO:0060089
GO:0060221
GO:0097719
GO:0120302
GO:0150103
GO:1904390
HMNXSV003040223
ILMN_1745537
PH_hs_0002922
TC01002960.hg
Z18859_rna1_at
g12652948_3p_at
Participates
as a member of
G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)
G-protein alpha (o/t2) [plasma membrane] (Homo sapiens)
as a component of
GNAT2:GTP [plasma membrane] (Homo sapiens)
Inferred To
gnat2 [plasma membrane]
(Danio rerio)
GNAT2 [plasma membrane]
(Bos taurus)
GNAT2 [plasma membrane]
(Canis familiaris)
GNAT2 [plasma membrane]
(Gallus gallus)
GNAT2 [plasma membrane]
(Sus scrofa)
Gnat2 [plasma membrane]
(Mus musculus)
Gnat2 [plasma membrane]
(Rattus norvegicus)
Ghost homologue of GNAT2 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_005263.1
,
XP_011539566.1
OpenTargets
ENSG00000134183
HPA
ENSG00000134183-GNAT2
GeneCards
P19087
Ensembl
ENST00000679935
,
ENSP00000505083
,
ENSP00000251337
,
ENSG00000134183
,
ENST00000351050
PRO
P19087
Pharos - Targets
P19087
Orphanet
16149
PDB
6N85
,
6N84
HMDB Protein
HMDBP11466
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