Reactome | GNAT1 [plasma membrane]

GNAT1 [plasma membrane]

Stable Identifier

R-HSA-167411

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

G protein alpha (T1), G(T1)

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Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR downstream signalling (Homo sapiens)
    - G alpha (i) signalling events (Homo sapiens)
      - G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Homo sapiens)
        
        G-alpha(t)-GTP [plasma membrane] (Homo sapiens)
        
        G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)
        
        GNAT1 [plasma membrane] (Homo sapiens)
        
        G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
        
        G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Homo sapiens)
        
        G-alpha(t)-GTP [plasma membrane] (Homo sapiens)
        
        G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)
        
        GNAT1 [plasma membrane] (Homo sapiens)
      - Opsins act as GEFs for G alpha-t (Homo sapiens)
        
        G-alpha(t):GDP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
        
        G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Homo sapiens)
        
        G-alpha(t)-GDP [plasma membrane] (Homo sapiens)
        
        G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)
        
        GNAT1 [plasma membrane] (Homo sapiens)
        
        G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
        
        G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Homo sapiens)
        
        G-alpha(t)-GTP [plasma membrane] (Homo sapiens)
        
        G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)
        
        GNAT1 [plasma membrane] (Homo sapiens)
      - Opsins binds G alpha-t (Homo sapiens)
        
        G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Homo sapiens)
        
        G-alpha(t)-GDP [plasma membrane] (Homo sapiens)
        
        G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)
        
        GNAT1 [plasma membrane] (Homo sapiens)
        
        G-alpha(t):GDP:G-beta-gamma:Opsins [plasma membrane] (Homo sapiens)
        
        G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Homo sapiens)
        
        G-alpha(t)-GDP [plasma membrane] (Homo sapiens)
        
        G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)
        
        GNAT1 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P11488 GNAT1

Gene Names

GNAT1, GNATR

Chain

initiator methionine:1, chain:2-350

Reference Genes

BioGPS Gene:2779 GNAT1

COSMIC (genes):GNAT1 GNAT1

CTD Gene:2779 GNAT1

dbSNP Gene:2779 GNAT1

ENSEMBL:ENSG00000114349 GNAT1

ENSEMBL:ENSG00000114349.10 GNAT1

HGNC:4393 GNAT1

KEGG Gene (Homo sapiens):2779 GNAT1

Monarch:2779 GNAT1

NCBI Gene:2779 GNAT1

OMIM:139330 GNAT1

UCSC:P11488 GNAT1

Reference Transcript

Other Identifiers

11739736_s_at

11740343_a_at

11740344_a_at

16940951

207514_PM_s_at

207514_s_at

214286_PM_at

214286_at

2622591

2622592

2622595

2622596

2622597

2622598

2622599

2622601

2622602

2622603

2622604

2622605

2622606

2622661

2779

34073_s_at

36085_at

8079919

A_14_P114750

A_23_P166884

A_24_P320036

GE80898

GO:0000035

GO:0000166

GO:0001580

GO:0001664

GO:0001750

GO:0001917

GO:0003824

GO:0003924

GO:0005525

GO:0005829

GO:0005834

GO:0005886

GO:0005929

GO:0007165

GO:0007186

GO:0007188

GO:0007601

GO:0007602

GO:0007603

GO:0008283

GO:0009416

GO:0009642

GO:0016020

GO:0016056

GO:0016324

GO:0016787

GO:0019001

GO:0019003

GO:0019901

GO:0022400

GO:0023052

GO:0030154

GO:0031683

GO:0032391

GO:0042462

GO:0042622

GO:0042995

GO:0043025

GO:0043226

GO:0046872

GO:0048856

GO:0050877

GO:0050896

GO:0050908

GO:0050917

GO:0051343

GO:0051344

GO:0060041

GO:0071257

GO:0097381

HMNXSV003037812

Hs.51147.1.S1_3p_a_at

Hs.51147.1.S1_3p_x_at

ILMN_1697315

ILMN_1750901

PH_hs_0003526

TC03000305.hg

g4504048_3p_a_at

Participates

as a member of

G-protein alpha (t) subunit [plasma membrane] (Homo sapiens)

Other forms of this molecule

N-(C12:0)-GNAT1 [photoreceptor disc membrane]

N-(C14:2)-GNAT1 [photoreceptor disc membrane]

N-(C14:1)-GNAT1 [photoreceptor disc membrane]

GNAT1 [photoreceptor disc membrane]

N-(C14:0)-GNAT1 [photoreceptor disc membrane]

GNAT1 (Met removed) [cytosol]

GNAT1 [cytosol]

Inferred To

GNAT1 [plasma membrane] (Bos taurus)

GNAT1 [plasma membrane] (Caenorhabditis elegans)

GNAT1 [plasma membrane] (Canis familiaris)

GNAT1 [plasma membrane] (Mus musculus)

GNAT1 [plasma membrane] (Sus scrofa)

Gnat1 [plasma membrane] (Rattus norvegicus)

wu:fk56e06 [plasma membrane] (Danio rerio)

Homologues of GNAT1 [plasma membrane] (Caenorhabditis elegans)

gnat1 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_000163.2, NP_653082.1

OpenTargets

ENSG00000114349

HPA

ENSG00000114349-GNAT1

GeneCards

P11488

Ensembl

ENST00000232461, ENSP00000387555, ENSG00000114349, ENST00000433068, ENSP00000232461

PRO

P11488

Pharos - Targets

P11488

Orphanet

16148

HMDB Protein

HMDBP02413

PDB

3RBQ