HIV elongation arrest and recovery

Stable Identifier
R-HSA-167287
Type
Pathway
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
nucleoplasm
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HIV elongation arrest and recovery
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RNA Pol II arrest is believed to be a result of irreversible backsliding of the enzyme by ~7-14 nucleotides. TFIIS reactivates arrested RNA Pol II by promoting the excision of nascent transcript ~7-14 nucleotides upstream of the 3' end.

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Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Created
Matthews, L  (2005-10-14)
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