PRLR activation

Stable Identifier
R-HSA-1671687
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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Ligand binding activates the PRLR, probably by causing a subtle conformational change (Broutin et al. 2010).

Literature References
PubMed ID Title Journal Year
20053995 Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2

Broutin, I, Jomain, JB, Tallet, E, van Agthoven, J, Raynal, B, Hoos, S, Kragelund, BB, Kelly, PA, Ducruix, A, England, P, Goffin, V

J Biol Chem 2010
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