DSIF:NELF:early elongation complex

Participants

components

• NELF complex [nucleoplasm] (Homo sapiens)
• RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (Homo sapiens)

Participant Of

input

• Abortive termination of HIV-1 early transcription elongation by DSIF:NELF
• Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex
• Hyperphosphorylation (Ser2) of RNA Pol II CTD by the P-TEFb(Cyclin T1:Cdk9) complex
• Limited elongation of the HIV-1 transcript

output

• Formation of DSIF:NELF:HIV-1 early elongation complex