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pro-beta-NGF homodimer transits to the golgi apparatus
Stable Identifier
R-HSA-167014
Type
Reaction [transition]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
,
Golgi lumen
ReviewStatus
5/5
Locations in the PathwayBrowser
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Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Expression and Processing of Neurotrophins (Homo sapiens)
NGF processing (Homo sapiens)
pro-beta-NGF homodimer transits to the golgi apparatus (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
From the endoplasmic reticulum, the pro-neurotrophins transit to the golgi apparatus, most likely via intermediate non-clathrin-coated transport vesicles, and finally accumulate in the trans-golgi network (TGN). In the TGN, two different types of secretory vesicles can be generated and filled with neurotrophins: regulated and constitutive secretory vesicles.
Participants
Input
pro-beta-NGF homodimer [endoplasmic reticulum lumen]
(Homo sapiens)
Output
pro-beta-NGF homodimer [Golgi lumen]
(Homo sapiens)
Participates
as an event of
NGF processing (Homo sapiens)
Inferred From
pro-beta-NGF homodimer transits to the golgi apparatus (Rattus norvegicus)
Authored
Nasi, S (2006-10-10)
Annibali, D (2006-10-10)
Created
© 2025
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