TLR4:LY96:LPS:CD14 [plasma membrane]

Stable Identifier
Homo sapiens
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
14517279 Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14

Kusumoto, S, Nagai, Y, Miyake, K, Takamura, N, Kusumoto, Y, Fukase, K, Saitoh, S, Adachi, Y, Akashi, S, Kikuchi, T, Kosugi, A, Wakabayashi, Y

J. Exp. Med. 2003
17803912 Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran

Park, BS, Oh, SC, Lee, H, Kim, JI, Kim, HM, Matsushima, N, Yoo, OJ, Lee, JO, Lee, J, Kim, SE, Enkhbayar, P

Cell 2007
19252480 The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex

Park, BS, Lee, H, Kim, HM, Song, DH, Lee, JO, Choi, BS

Nature 2009
11274165 Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2

Tobias, PS, da Silva Correia, J, Ulevitch, RJ, Christen, U, Soldau, K

J. Biol. Chem. 2001
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