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UCP2 [mitochondrial inner membrane]
Stable Identifier
R-HSA-166392
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
Mitochondrial uncoupling protein 2
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Mitochondrial Uncoupling (Homo sapiens)
The fatty acid cycling model (Homo sapiens)
FA anion diffuses laterally to UCP (Homo sapiens)
FA anion:UCP dimer "head-in" complex [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
UCP2 [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
UCP2 [mitochondrial inner membrane] (Homo sapiens)
FA anion flip-flops to the opposite surface (Homo sapiens)
FA anion:UCP dimer "head-out" complex [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
UCP2 [mitochondrial inner membrane] (Homo sapiens)
FA anion:UCP dimer "head-in" complex [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
UCP2 [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
UCP2 [mitochondrial inner membrane] (Homo sapiens)
The FA anion diffuses away laterally from UCP (Homo sapiens)
FA anion:UCP dimer "head-out" complex [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
UCP2 [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
UCP2 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P55851 UCP2
Gene Names
UCP2, SLC25A8
Chain
chain:1-309
Reference Genes
BioGPS Gene:7351 UCP2
COSMIC (genes):UCP2 UCP2
CTD Gene:7351 UCP2
dbSNP Gene:7351 UCP2
ENSEMBL:ENSG00000175567 UCP2
HGNC:12518 UCP2
KEGG:hsa:7351 UCP2
Monarch:7351 UCP2
NCBI Gene:7351 UCP2
OMIM:601693 UCP2
UCSC:P55851 UCP2
Reference Transcript
RefSeq:NM_003355.2 UCP2
Other Identifiers
11729159_a_at
11729160_x_at
11754461_s_at
11757654_x_at
16741969
208997_PM_s_at
208997_s_at
208998_PM_at
208998_at
3381705
3381818
3381819
3381820
3381821
3381822
3381823
3381824
3381825
3381826
3381827
3381828
3381829
3381830
3381831
3381832
3381833
3381834
37591_at
7351
7950307
A_23_P47704
GE59585
GO:0000266
GO:0000303
GO:0001666
GO:0005215
GO:0005515
GO:0005739
GO:0005743
GO:0005975
GO:0006091
GO:0006096
GO:0006520
GO:0006541
GO:0006839
GO:0007005
GO:0008271
GO:0009409
GO:0009749
GO:0015078
GO:0015108
GO:0015131
GO:0015140
GO:0015183
GO:0015297
GO:0015698
GO:0015740
GO:0015909
GO:0016020
GO:0017077
GO:0019003
GO:0030154
GO:0030225
GO:0031966
GO:0032869
GO:0032870
GO:0034198
GO:0042803
GO:0043066
GO:0043226
GO:0043524
GO:0048856
GO:0051881
GO:0055085
GO:0055086
GO:0061179
GO:0070542
GO:0070778
GO:0071284
GO:0071333
GO:0071423
GO:0071548
GO:0072593
GO:0097421
GO:0110099
GO:0120162
GO:0140787
GO:1901135
GO:1902356
GO:1902358
GO:1902476
GO:1902600
GO:1990542
GO:1990845
HMNXSV003038545
ILMN_1685625
PH_hs_0004639
TC11002074.hg
U94592_at
g1877473_3p_a_at
Participates
as a member of
UCP [mitochondrial inner membrane] (Homo sapiens)
Inferred To
ucp2 [mitochondrial inner membrane]
(Danio rerio)
ucp2 [mitochondrial inner membrane]
(Xenopus tropicalis)
UCP2 [mitochondrial inner membrane]
(Bos taurus)
UCP2 [mitochondrial inner membrane]
(Canis familiaris)
UCP2 [mitochondrial inner membrane]
(Sus scrofa)
Ucp2 [mitochondrial inner membrane]
(Mus musculus)
Ucp2 [mitochondrial inner membrane]
(Rattus norvegicus)
UCP [mitochondrial inner membrane]
(Gallus gallus)
Cross References
Guide to Pharmacology - Targets
1067
ENSEMBL
ENST00000663595
,
ENSG00000175567
,
ENST00000310473
,
ENSP00000312029
,
ENSP00000499695
OpenTargets
ENSG00000175567
GeneCards
UCP2
HPA
ENSG00000175567-UCP2
PRO
P55851
Pharos - Targets
P55851
Orphanet
UCP2
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P20930 FLG
2
FLG(?-?) [cytosol]
(R-HSA-6810859)
FLG(1-4061) [cytosol]
(R-HSA-8849818)
0.527
2
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