FA anion diffuses laterally to UCP

Stable Identifier
R-HSA-166220
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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A FA anion diffuses laterally within the membrane towards UCP. The membrane potential drives the FA anion to an energy well halfway up on UCP. The electric field created by the redox-linked proton ejection drives the head group to the energy well.

Literature References
PubMed ID Title Journal Year
8576230 On the mechanism of fatty acid-induced proton transport by mitochondrial uncoupling protein

Garlid, KD, Orosz, DE, Modriansky, M, Vassanelli, S, Jezek, P

J Biol Chem 1996
11709078 Mechanism of uncoupling protein action

Garlid, KD, Jaburek, M, Jezek, P

Biochem Soc Trans 2001
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Created