FA anion diffuses laterally to UCP

Stable Identifier
R-HSA-166220
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
A FA anion diffuses laterally within the membrane towards UCP. The membrane potential drives the FA anion to an energy well halfway up on UCP. The electric field created by the redox-linked proton ejection drives the head group to the energy well.
Literature References
PubMed ID Title Journal Year
11709078 Mechanism of uncoupling protein action

Garlid, KD, Jezek, P, Jaburek, M

Biochem Soc Trans 2001
8576230 On the mechanism of fatty acid-induced proton transport by mitochondrial uncoupling protein

Garlid, KD, Jezek, P, Modriansky, M, Orosz, DE, Vassanelli, S

J Biol Chem 1996
Participants
Participates
Orthologous Events
Created
Cite Us!