FA anion diffuses laterally to UCP

Stable Identifier
R-HSA-166220
Type
Reaction
Species
Homo sapiens
Compartment
mitochondrial inner membrane
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FA anion diffuses laterally to UCP
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A FA anion diffuses laterally within the membrane towards UCP. The membrane potential drives the FA anion to an energy well halfway up on UCP. The electric field created by the redox-linked proton ejection drives the head group to the energy well.

Literature References
PubMed ID Title Journal Year
11709078 Mechanism of uncoupling protein action

Garlid, KD, Jezek, P, Jaburek, M

Biochem Soc Trans 2001
8576230 On the mechanism of fatty acid-induced proton transport by mitochondrial uncoupling protein

Garlid, KD, Jezek, P, Modriansky, M, Orosz, DE, Vassanelli, S

J Biol Chem 1996
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Orthologous Events
FA anion diffuses laterally to UCP (Bos taurus)
FA anion diffuses laterally to UCP (Caenorhabditis elegans)
FA anion diffuses laterally to UCP (Canis familiaris)
FA anion diffuses laterally to UCP (Danio rerio)
FA anion diffuses laterally to UCP (Drosophila melanogaster)
FA anion diffuses laterally to UCP (Gallus gallus)
FA anion diffuses laterally to UCP (Mus musculus)
FA anion diffuses laterally to UCP (Rattus norvegicus)
FA anion diffuses laterally to UCP (Sus scrofa)
FA anion diffuses laterally to UCP (Xenopus tropicalis)
Created
Jassal, B  (2005-08-22)
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