FA anion flip-flops to the opposite surface

Stable Identifier
R-HSA-166214
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
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FA anion flip-flops to the opposite surface
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The FA anion which was facing the matrix side of the inner mitochondrial membrane now flip-flops over to the intermembrane space-side of the membrane.

Literature References
PubMed ID Title Journal Year
8576230 On the mechanism of fatty acid-induced proton transport by mitochondrial uncoupling protein

Garlid, KD, Orosz, DE, Modriansky, M, Vassanelli, S, Jezek, P

J Biol Chem 1996
11709078 Mechanism of uncoupling protein action

Garlid, KD, Jaburek, M, Jezek, P

Biochem Soc Trans 2001
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
anion transmembrane transporter activity of FA anion:UCP dimer "head-in" complex [mitochondrial inner membrane]
Physical Entity
FA anion:UCP dimer "head-in" complex [mitochondrial inner membrane]
Activity
anion transmembrane transporter activity (0008509)
Orthologous Events
FA anion flip-flops to the opposite surface (Bos taurus)
FA anion flip-flops to the opposite surface (Caenorhabditis elegans)
FA anion flip-flops to the opposite surface (Canis familiaris)
FA anion flip-flops to the opposite surface (Danio rerio)
FA anion flip-flops to the opposite surface (Drosophila melanogaster)
FA anion flip-flops to the opposite surface (Gallus gallus)
FA anion flip-flops to the opposite surface (Mus musculus)
FA anion flip-flops to the opposite surface (Rattus norvegicus)
FA anion flip-flops to the opposite surface (Sus scrofa)
FA anion flip-flops to the opposite surface (Xenopus tropicalis)
Created
Jassal, B  (2005-08-22)