FA anion flip-flops to the opposite surface

Stable Identifier
R-HSA-166214
Type
Reaction
Species
Homo sapiens
Compartment
mitochondrial inner membrane
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FA anion flip-flops to the opposite surface
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The FA anion which was facing the matrix side of the inner mitochondrial membrane now flip-flops over to the intermembrane space-side of the membrane.

Literature References
PubMed ID Title Journal Year
11709078 Mechanism of uncoupling protein action

Garlid, KD, Jezek, P, Jaburek, M

Biochem Soc Trans 2001
8576230 On the mechanism of fatty acid-induced proton transport by mitochondrial uncoupling protein

Garlid, KD, Jezek, P, Modriansky, M, Orosz, DE, Vassanelli, S

J Biol Chem 1996
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Output
Participates
as an event of
Catalyst Activity

anion transmembrane transporter activity of FA anion:UCP dimer "head-in" complex [mitochondrial inner membrane]

Physical Entity
FA anion:UCP dimer "head-in" complex [mitochondrial inner membrane] (Homo sapiens)
Activity
anion transmembrane transporter activity (GO:0008509)
Orthologous Events
FA anion flip-flops to the opposite surface (Bos taurus)
FA anion flip-flops to the opposite surface (Caenorhabditis elegans)
FA anion flip-flops to the opposite surface (Canis familiaris)
FA anion flip-flops to the opposite surface (Danio rerio)
FA anion flip-flops to the opposite surface (Drosophila melanogaster)
FA anion flip-flops to the opposite surface (Gallus gallus)
FA anion flip-flops to the opposite surface (Mus musculus)
FA anion flip-flops to the opposite surface (Rattus norvegicus)
FA anion flip-flops to the opposite surface (Sus scrofa)
FA anion flip-flops to the opposite surface (Xenopus tropicalis)
Created
Jassal, B  (2005-08-22)
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