Reactome | Glycosphingolipid metabolism

Glycosphingolipid metabolism

Stable Identifier

R-HSA-1660662

Type

Pathway

Species

Homo sapiens

Compartment

Golgi lumen, Golgi membrane, endoplasmic reticulum lumen, endoplasmic reticulum membrane, lysosomal lumen, lysosomal membrane, multivesicular body lumen, multivesicular body, internal vesicle, multivesicular body, internal vesicle membrane, plasma membrane

ReviewStatus

5/5

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The steps involved in the synthesis and degradation of glycosphingolipids (sphingolipids with one or more sugars attached) are annotated here (the topic is reviewed by Gault et al. 2010; Sandhoff & Sandhoff, 2018; Sandhoff et al, 2018).

Literature References

PubMed ID	Title	Journal	Year
20919643	An overview of sphingolipid metabolism: from synthesis to breakdown Gault, CR, Obeid, LM, Hannun, YA	Adv Exp Med Biol	2010
29747811	Ganglioside Metabolism in Health and Disease Sandhoff, R, Schulze, H, Sandhoff, K	Prog Mol Biol Transl Sci	2018
29802621	Emerging concepts of ganglioside metabolism Sandhoff, R, Sandhoff, K	FEBS Lett	2018