PIPs transport between plasma and early endosome membranes

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R-HSA-1660524
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Pathway
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Homo sapiens
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The phosphoinositide phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) translocates from the plasma membrane to the early endosome membrane (Watt et al. 2004, Ivetac et al. 2005).

Literature References
PubMed ID Title Journal Year
15716355 The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane

Luff, S, Majerus, PW, Kisseleva, MV, Rowe, T, Zhang, XM, Tiganis, T, Munday, AD, Ivetac, I, Mitchell, CA, Whisstock, JC

Mol Biol Cell 2005
14604433 Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy

Leslie, NR, Kimber, WA, Lucocq, JM, Downes, CP, Watt, SA, Fleming, IN

Biochem J 2004
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