PIPs transport between early and late endosome membranes

Stable Identifier
R-HSA-1660502
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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PIPs transport between early and late endosome membranes
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The maturation of the early endosome compartment into a late endosome is triggered by the presence of phosphoinositide phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) (Cabezas et al. 2006, Ikonomov et al. 2006, Ikonomov et al. 2001).
Literature References
PubMed ID Title Journal Year
11285266 Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve

Sbrissa, D, Shisheva, A, Ikonomov, OC

J Biol Chem 2001
16510848 Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion

Sbrissa, D, Shisheva, A, Ikonomov, OC

Am J Physiol Cell Physiol 2006
16448788 Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1

Stenmark, H, Cabezas, A, Pattni, K

Gene 2006
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Event Information
Go Biological Process
phospholipid translocation (0045332)
Authored
Williams, MG  (2011-10-18)
Reviewed
Wakelam, M  (2012-05-14)
Created
Williams, MG  (2011-10-13)
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