PIPs transport between early and late endosome membranes

Stable Identifier
R-HSA-1660502
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this pathway in the Pathway Browser

The maturation of the early endosome compartment into a late endosome is triggered by the presence of phosphoinositide phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) (Cabezas et al. 2006, Ikonomov et al. 2006, Ikonomov et al. 2001).

Literature References
PubMed ID Title Journal Year
11285266 Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve

Sbrissa, D, Shisheva, A, Ikonomov, OC

J Biol Chem 2001
16510848 Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion

Sbrissa, D, Shisheva, A, Ikonomov, OC

Am J Physiol Cell Physiol 2006
16448788 Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1

Stenmark, H, Cabezas, A, Pattni, K

Gene 2006
Participants
Participates
Event Information
Go Biological Process
Authored
Reviewed
Created
Cite Us!