Expression of Mevalonate Kinase (MVK)

Stable Identifier
R-HSA-1655846
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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The MVK gene is transcribed to yield mRNA and the mRNA is translated to yield protein.

Literature References
PubMed ID Title Journal Year
1377680 Molecular cloning of human mevalonate kinase and identification of a missense mutation in the genetic disease mevalonic aciduria

Schafer, BL, Bishop, RW, Kratunis, VJ, Kalinowski, SS, Mosley, ST, Gibson, KM, Tanaka, RD

J Biol Chem 1992
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Summation

SREBF1A (SREBP1A) and SREBF2 (SREBP2) bind the promoter of the Mevalonate kinase (MVK) gene and enhance transcription (Sakakura et al. 2001, Reed et al. 2008, reviewed in Horton et al. 2002).

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