SREBF1A (SREBP1A) and SREBF1C (SREBP1C) bind the promoter of the Acetyl-CoA carboxylase 1 (ACACA, ACC1) gene and enhance transcription (Shimano et al. 1996, Magana et al. 1997, Shimano et al. 1997, Shimano et al. 1999, Rome et al. 2008, reviewed in Horton et al. 2002).
The ACACA gene is transcribed to yield mRNA and the mRNA is translated to yield protein.