Expression of Glycerol-3-phosphate Acyltransferase (GPAM, GPAT)

Stable Identifier
R-HSA-1655837
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, mitochondrial outer membrane
ReviewStatus
5/5
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Expression of Glycerol-3-phosphate Acyltransferase (GPAM, GPAT)
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As inferred from mouse, SREBF1A (SREBP1A) and SREBF1C (SREBP1C) bind the promoter of the Glycerol-3-phosphate acyltransferase gene (GPAM, GPAT) and enhance transcription (Ericsson et al. 1997, Shimano et al. 1999, Griffin et al. 2007, Yoshida et al. 2009, reviewed in Horton et al. 2002). The GPAM gene is transcribed to yield mRNA and the mRNA is translated to yield protein.
Literature References
PubMed ID Title Journal Year
20719759 Expression and regulation of GPAT isoforms in cultured human keratinocytes and rodent epidermis

Lu, B, Feingold, KR, Kim, P, Moser, A, Grunfeld, C, Elias, PM, Jiang, YJ

J Lipid Res 2010
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Output
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This event is regulated
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Regulator
SREBP1A,1C:NF-Y:GPAM gene [nucleoplasm] (Homo sapiens)
Authored
May, B  (2011-09-28)
Reviewed
Liang, G  (2012-08-26)
Created
May, B  (2011-10-13)
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