Expression of ELOVL6

Stable Identifier
R-HSA-1655835
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, endoplasmic reticulum membrane
ReviewStatus
5/5
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Expression of ELOVL6
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The ELOVL6 gene is transcribed to yield mRNA and the mRNA is translated to yield protein. As inferred from mouse, SREBF1A/1C/2 (SREBP1A/1C/2) bind the promoter of the ELOVL6 gene and enhances transcription (Moon et al. 2001, Matsuzaka et al. 2002, Kumadaki et al. 2008).
Literature References
PubMed ID Title Journal Year
20937905 ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis

Ohno, Y, Suto, S, Yamanaka, M, Mizutani, Y, Mitsutake, S, Igarashi, Y, Sassa, T, Kihara, A

Proc Natl Acad Sci U S A 2010
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
positive regulation of transcription by RNA polymerase II (0045944)
This event is regulated
Positively by
Regulator
SREBP1A,1C,2:ELOVL6 gene [nucleoplasm] (Homo sapiens)
Authored
May, B  (2011-09-28)
Reviewed
Liang, G  (2012-08-26)
Created
May, B  (2011-10-13)
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